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Dextran Chemistry Stability


Dry Substance Dextran Powder
Dextran fractions are stable for more than 5 years when stored as a dry substance Dextran powder in well-sealed containers at room temperature. Dextran powder will slowly absorb moisture when exposed to air or when stored in non-air tight containers.

Dextran Solutions and Sterilization
Dextran solutions may be sterilized by heating in an autoclave. These solutions are stable for many years and are best stored at constant temperature. The optimal pH for storage is between 6–7. However, Dextran is stable at ambient temperatures for extended periods in the pH range 4–10. Other techniques for sterilization of Dextran solutions, for example irradiation, may lead to degradation.

During autoclaving a slight decrease in pH and a slight yellowing may be observed, which does not affect Dextran fraction solutions or performance. The sterilization of Dextran solutions does not affect the molecular weight distribution of the Dextran.


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Pharmacosmos is the only dextran manufacturer holding certificates from the US FDA and European Directorate for the Quality of Medicines (EDQM)

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Quality Delivered

Pharmacosmos delivers a unique dextran quality through a production technology that completely avoids the use of organic solvents and a quality system that meets the strictest cGMP standards for human medicines

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Global Service

Pharmacosmos sells and ships directly to clients everywhere in the World. We deliver Pharmaceutical Quality Dextran of the highest standards, including those of the European Pharmacopoeia (EP), the United States Pharmacopoeia (USP), and the Japanese Pharmacopoeia (JP).

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