The dextran molecule is known to benefit on structural stability of freeze-dried products, protein stability and the recovery of enzyme activity after freeze-drying.
Dextran Product commonly used in Protein Stabilization are Dextran 1, Dextran 5, Dextran 10, Dextran 40, Dextran 70 and Dextran 500
Nonadditive effects of mixed crowding on protein stability
Link to study
Effect of dextran on protein stability and conformation attributed to macromolecular crowding
Link to article
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Anne-Marie J. Ørkild
Director, International Sales and Business Carbohydrates
Phone: +45 59 48 59 86 (direct)
Pharmacosmos is the only dextran manufacturer holding certificates from the US FDA and European Directorate for the Quality of Medicines (EDQM)
Pharmacosmos delivers a unique dextran quality through a production technology that completely avoids the use of organic solvents and a quality system that meets the strictest cGMP standards for human medicines
Pharmacosmos sells and ships directly to clients everywhere in the World. We deliver Pharmaceutical Quality Dextran of the highest standards, including those of the European Pharmacopoeia (EP), the United States Pharmacopoeia (USP), and the Japanese Pharmacopoeia (JP).