Pharmacosmos Carboxymethyl-Dextran (CM-Dextran) are based on Pharmacosmos’ world-leading Dextran products, and Pharmacosmos CM-Dextran are also produced at Pharmacosmos’ state-of-the-art, GMP-approved facility in Denmark.
As a natural consequence of Pharmacosmos’ commitment to quality, Pharmacosmos CM-Dextran are developed and manufactured according to the same advanced standards and requirements of the highest quality as applied in the development and manufacturing of our world-leading Dextran products.
CM-Dextran is made by reacting dextran with monochloric acid under alkaline conditions. The reaction is illustrated in Fig. 1 below. CM-Dextran is a polyanion in which the content of carboxyl groups is in the range 3% - 10%; corresponding to one carboxyl group for every 2.5 glucose units or less. The pKa value of the carboxyl group is approximately 8.2.
Fig. 1: CM-Dextran
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Anne-Marie J. Ørkild
Director, International Sales and Business Carbohydrates
Phone: +45 59 48 59 86 (direct)
Pharmacosmos is the only dextran manufacturer holding certificates from the US FDA and European Directorate for the Quality of Medicines (EDQM)
Pharmacosmos delivers a unique dextran quality through a production technology that completely avoids the use of organic solvents and a quality system that meets the strictest cGMP standards for human medicines
Pharmacosmos sells and ships directly to clients everywhere in the World. We deliver Pharmaceutical Quality Dextran of the highest standards, including those of the European Pharmacopoeia (EP), the United States Pharmacopoeia (USP), and the Japanese Pharmacopoeia (JP).